Genetic Incorporation of Seven ortho-Substituted Phenylalanine Derivatives

[Image: see text] Seven phenylalanine derivatives with small ortho substitutions were genetically encoded in Escherichia coli and mammalian cells at an amber codon using a previously reported, rationally designed pyrrolysyl-tRNA synthetase mutant (PylRS(N346A/C348A)) coupled with tRNA(CUA)(Pyl). Ort...

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Detalles Bibliográficos
Autores principales: Tharp, Jeffery M., Wang, Yane-Shih, Lee, Yan-Jiun, Yang, Yanyan, Liu, Wenshe R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997995/
https://www.ncbi.nlm.nih.gov/pubmed/24451054
http://dx.doi.org/10.1021/cb400917a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997995/
https://www.ncbi.nlm.nih.gov/pubmed/24451054
http://dx.doi.org/10.1021/cb400917a

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