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Dual Inhibitory Pathways of Metallofullerenol Gd@C(82)(OH)(22) on Matrix Metalloproteinase-2: Molecular insight into drug-like nanomedicine

Cancer metastasis is an important criterion to evaluate tumor malignancy. Matrix metalloproteinases (MMPs) play a crucial role in cancer proliferation and migration by virtue of their proteolytic functions in angiogenesis and extracelluar matrix (ECM) degradation, making them potential targets of an...

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Detalles Bibliográficos
Autores principales: Kang, Seung-gu, Araya-Secchi, Raul, Wang, Deqiang, Wang, Bo, Huynh, Tien, Zhou, Ruhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998016/
https://www.ncbi.nlm.nih.gov/pubmed/24758941
http://dx.doi.org/10.1038/srep04775