Microglial Cx3cr1 knockout reduces prion disease incubation time in mice

BACKGROUND: Microglia are resident mononuclear phagocytes of the brain that become activated in response to insults including neurodegenerative diseases such as Alzheimer’s disease, Parkinson’s disease and prion disease. In the central nervous system the chemokine Cx3cl1 (Fractalkine) is expressed b...

Descripción completa

Detalles Bibliográficos
Autores principales: Grizenkova, Julia, Akhtar, Shaheen, Brandner, Sebastian, Collinge, John, Lloyd, Sarah E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998043/
https://www.ncbi.nlm.nih.gov/pubmed/24655482
http://dx.doi.org/10.1186/1471-2202-15-44

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998043/
https://www.ncbi.nlm.nih.gov/pubmed/24655482
http://dx.doi.org/10.1186/1471-2202-15-44

Ejemplares similares