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Structural determinants of human ζ-globin mRNA stability

BACKGROUND: The normal accumulation of adult α and β globins in definitive erythrocytes is critically dependent upon processes that ensure that the cognate mRNAs are maintained at high levels in transcriptionally silent, but translationally active progenitor cells. The impact of these post-transcrip...

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Detalles Bibliográficos
Autores principales: He, Zhenning, Song, Decheng, van Zalen, Sebastiaan, Russell, J Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998057/
https://www.ncbi.nlm.nih.gov/pubmed/24751163
http://dx.doi.org/10.1186/1756-8722-7-35