Fidelity of end joining in mammalian episomes and the impact of Metnase on joint processing

BACKGROUND: Double Stranded Breaks (DSBs) are the most serious form of DNA damage and are repaired via homologous recombination repair (HRR) or non-homologous end joining (NHEJ). NHEJ predominates in mammalian cells at most stages of the cell cycle, and it is viewed as ‘error-prone’, although this n...

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Detalles Bibliográficos
Autores principales: Rath, Abhijit, Hromas, Robert, De Benedetti, Arrigo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998112/
https://www.ncbi.nlm.nih.gov/pubmed/24655462
http://dx.doi.org/10.1186/1471-2199-15-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998112/
https://www.ncbi.nlm.nih.gov/pubmed/24655462
http://dx.doi.org/10.1186/1471-2199-15-6

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