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Fidelity of end joining in mammalian episomes and the impact of Metnase on joint processing

BACKGROUND: Double Stranded Breaks (DSBs) are the most serious form of DNA damage and are repaired via homologous recombination repair (HRR) or non-homologous end joining (NHEJ). NHEJ predominates in mammalian cells at most stages of the cell cycle, and it is viewed as ‘error-prone’, although this n...

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Detalles Bibliográficos
Autores principales:	Rath, Abhijit, Hromas, Robert, De Benedetti, Arrigo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998112/ https://www.ncbi.nlm.nih.gov/pubmed/24655462 http://dx.doi.org/10.1186/1471-2199-15-6

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