Sitagliptin prevents aggravation of endocrine and exocrine pancreatic damage in the Zucker Diabetic Fatty rat - focus on amelioration of metabolic profile and tissue cytoprotective properties

BACKGROUND: The purpose of this study was to investigate some of the possible mechanisms underlying the protective effects of a dipeptidyl peptidase IV (DPP-IV) inhibitor, sitagliptin, on pancreatic tissue in an animal model of type 2 diabetes mellitus (T2DM), the Zucker Diabetic Fatty (ZDF) rat, fo...

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Detalles Bibliográficos
Autores principales: Mega, Cristina, Vala, Helena, Rodrigues-Santos, Paulo, Oliveira, Jorge, Teixeira, Frederico, Fernandes, Rosa, Reis, Flávio, de Lemos, Edite Teixeira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998187/
https://www.ncbi.nlm.nih.gov/pubmed/24650557
http://dx.doi.org/10.1186/1758-5996-6-42

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998187/
https://www.ncbi.nlm.nih.gov/pubmed/24650557
http://dx.doi.org/10.1186/1758-5996-6-42

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