Cargando…
The lifelong maintenance of mesencephalic dopaminergic neurons by Nurr1 and engrailed
Specific vulnerability and degeneration of the dopaminergic neurons in the substantia nigra pars compacta of the midbrain is the pathological hallmark of Parkinson’s disease. A number of transcription factors regulate the birth and development of this set of neurons and some remain constitutively ex...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998737/ https://www.ncbi.nlm.nih.gov/pubmed/24685177 http://dx.doi.org/10.1186/1423-0127-21-27 |