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Prophylactic cannabinoid administration blocks the development of paclitaxel-induced neuropathic nociception during analgesic treatment and following cessation of drug delivery

BACKGROUND: Chemotherapeutic treatment results in chronic pain in an estimated 30-40 percent of patients. Limited and often ineffective treatments make the need for new therapeutics an urgent one. We compared the effects of prophylactic cannabinoids as a preventative strategy for suppressing develop...

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Detalles Bibliográficos
Autores principales: Rahn, Elizabeth J, Deng, Liting, Thakur, Ganesh A, Vemuri, Kiran, Zvonok, Alexander M, Lai, Yvonne Y, Makriyannis, Alexandros, Hohmann, Andrea G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998744/
https://www.ncbi.nlm.nih.gov/pubmed/24742127
http://dx.doi.org/10.1186/1744-8069-10-27