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Molecular Dosimetry of Endogenous and Exogenous O(6)-Methyl-dG and N7-Methyl-G Adducts Following Low Dose [D(3)]-Methylnitrosourea Exposures in Cultured Human Cells
[Image: see text] For DNA-reactive chemicals, a low dose linear assessment of cancer risk is the science policy default. In the present study, we quantitated the endogenous and exogenous N7-methyl-G and O(6)-methyl-dG adducts in human lymphoblastoid cells exposed to low dose [D(3)]-methylnitrosourea...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American
Chemical
Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998766/ https://www.ncbi.nlm.nih.gov/pubmed/24628573 http://dx.doi.org/10.1021/tx5000602 |