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Molecular Dosimetry of Endogenous and Exogenous O(6)-Methyl-dG and N7-Methyl-G Adducts Following Low Dose [D(3)]-Methylnitrosourea Exposures in Cultured Human Cells

[Image: see text] For DNA-reactive chemicals, a low dose linear assessment of cancer risk is the science policy default. In the present study, we quantitated the endogenous and exogenous N7-methyl-G and O(6)-methyl-dG adducts in human lymphoblastoid cells exposed to low dose [D(3)]-methylnitrosourea...

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Detalles Bibliográficos
Autores principales:	Sharma, Vyom, Collins, Leonard B., Clement, Jean M., Zhang, Zhenfa, Nakamura, Jun, Swenberg, James A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998766/ https://www.ncbi.nlm.nih.gov/pubmed/24628573 http://dx.doi.org/10.1021/tx5000602

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