Cargando…

EB1 enables spindle microtubules to regulate centromeric recruitment of Aurora B

The Aurora B kinase coordinates kinetochore–microtubule attachments with spindle checkpoint signaling on each mitotic chromosome. We find that EB1, a microtubule plus end–tracking protein, is required to enrich Aurora B at inner centromeres in a microtubule-dependent manner. This regulates phosphory...

Descripción completa

Detalles Bibliográficos
Autores principales: Banerjee, Budhaditya, Kestner, Cortney A., Stukenberg, P. Todd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998792/
https://www.ncbi.nlm.nih.gov/pubmed/24616220
http://dx.doi.org/10.1083/jcb.201307119