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HookA is a novel dynein–early endosome linker critical for cargo movement in vivo

Cytoplasmic dynein transports membranous cargoes along microtubules, but the mechanism of dynein–cargo interaction is unclear. From a genetic screen, we identified a homologue of human Hook proteins, HookA, as a factor required for dynein-mediated early endosome movement in the filamentous fungus As...

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Detalles Bibliográficos
Autores principales: Zhang, Jun, Qiu, Rongde, Arst, Herbert N., Peñalva, Miguel A., Xiang, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998793/
https://www.ncbi.nlm.nih.gov/pubmed/24637327
http://dx.doi.org/10.1083/jcb.201308009