Cargando…
HookA is a novel dynein–early endosome linker critical for cargo movement in vivo
Cytoplasmic dynein transports membranous cargoes along microtubules, but the mechanism of dynein–cargo interaction is unclear. From a genetic screen, we identified a homologue of human Hook proteins, HookA, as a factor required for dynein-mediated early endosome movement in the filamentous fungus As...
Autores principales: | Zhang, Jun, Qiu, Rongde, Arst, Herbert N., Peñalva, Miguel A., Xiang, Xin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998793/ https://www.ncbi.nlm.nih.gov/pubmed/24637327 http://dx.doi.org/10.1083/jcb.201308009 |
Ejemplares similares
-
Cargo-Mediated Activation of Cytoplasmic Dynein in vivo
por: Xiang, Xin, et al.
Publicado: (2020) -
Hook is an adapter that coordinates kinesin-3 and dynein cargo attachment on early endosomes
por: Bielska, Ewa, et al.
Publicado: (2014) -
LIS1 regulates cargo-adapter–mediated activation of dynein by overcoming its autoinhibition in vivo
por: Qiu, Rongde, et al.
Publicado: (2019) -
Kinesin-1 autoinhibition facilitates the initiation of dynein cargo transport
por: Qiu, Rongde, et al.
Publicado: (2022) -
Discovery of a vezatin-like protein for dynein-mediated early endosome transport
por: Yao, Xuanli, et al.
Publicado: (2015)