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Dual-mode regulation of the APC/C by CDK1 and MAPK controls meiosis I progression and fidelity

Female meiosis is driven by the activities of two major kinases, cyclin-dependent kinase 1 (Cdk1) and mitogen-activated protein kinase (MAPK). To date, the role of MAPK in control of meiosis is thought to be restricted to maintaining metaphase II arrest through stabilizing Cdk1 activity. In this pap...

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Detalles Bibliográficos
Autores principales: Nabti, Ibtissem, Marangos, Petros, Bormann, Jenny, Kudo, Nobuaki R., Carroll, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998794/
https://www.ncbi.nlm.nih.gov/pubmed/24637322
http://dx.doi.org/10.1083/jcb.201305049