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Kruppel-like factor 4 attenuates osteoblast formation, function, and cross talk with osteoclasts
Osteoblasts not only control bone formation but also support osteoclast differentiation. Here we show the involvement of Kruppel-like factor 4 (KLF4) in the differentiation of osteoclasts and osteoblasts. KLF4 was down-regulated by 1α,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3)) in osteoblasts. Overex...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998795/ https://www.ncbi.nlm.nih.gov/pubmed/24616223 http://dx.doi.org/10.1083/jcb.201308102 |