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ER-associated degradation: Protein quality control and beyond

Even with the assistance of many cellular factors, a significant fraction of newly synthesized proteins ends up misfolded. Cells evolved protein quality control systems to ensure that these potentially toxic species are detected and eliminated. The best characterized of these pathways, the ER-associ...

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Detalles Bibliográficos
Autores principales: Ruggiano, Annamaria, Foresti, Ombretta, Carvalho, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998802/
https://www.ncbi.nlm.nih.gov/pubmed/24637321
http://dx.doi.org/10.1083/jcb.201312042