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ER-associated degradation: Protein quality control and beyond
Even with the assistance of many cellular factors, a significant fraction of newly synthesized proteins ends up misfolded. Cells evolved protein quality control systems to ensure that these potentially toxic species are detected and eliminated. The best characterized of these pathways, the ER-associ...
Autores principales: | Ruggiano, Annamaria, Foresti, Ombretta, Carvalho, Pedro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998802/ https://www.ncbi.nlm.nih.gov/pubmed/24637321 http://dx.doi.org/10.1083/jcb.201312042 |
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