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LTP requires a reserve pool of glutamate receptors independent of subunit type

Long-term potentiation (LTP) of synaptic transmission is thought to be a key cellular mechanism underlying memory formation. A widely accepted model posits that LTP requires the cytoplasmic tail of the AMPA receptor subunit GluA1. To find the minimum necessary requirement of the GluA1 C-tail for LTP...

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Detalles Bibliográficos
Autores principales: Granger, Adam J., Shi, Yun, Lu, Wei, Cerpas, Manuel, Nicoll, Roger A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998843/
https://www.ncbi.nlm.nih.gov/pubmed/23235828
http://dx.doi.org/10.1038/nature11775