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Electrosprayed core–shell solid dispersions of acyclovir fabricated using an epoxy-coated concentric spray head
A novel structural solid dispersion (SD) taking the form of core–shell microparticles for poorly water-soluble drugs is reported for the first time. Using polyvinylpyrrolidone (PVP) as a hydrophilic polymer matrix, the SDs were fabricated using coaxial electrospraying (characterized by an epoxy-coat...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998863/ https://www.ncbi.nlm.nih.gov/pubmed/24790437 http://dx.doi.org/10.2147/IJN.S59516 |