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Electrosprayed core–shell solid dispersions of acyclovir fabricated using an epoxy-coated concentric spray head

A novel structural solid dispersion (SD) taking the form of core–shell microparticles for poorly water-soluble drugs is reported for the first time. Using polyvinylpyrrolidone (PVP) as a hydrophilic polymer matrix, the SDs were fabricated using coaxial electrospraying (characterized by an epoxy-coat...

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Detalles Bibliográficos
Autores principales:	Liu, Zhe-Peng, Cui, Lei, Yu, Deng-Guang, Zhao, Zhuan-Xia, Chen, Lan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2014
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998863/ https://www.ncbi.nlm.nih.gov/pubmed/24790437 http://dx.doi.org/10.2147/IJN.S59516

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