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Systematic Evaluation of Methods for Integration of Transcriptomic Data into Constraint-Based Models of Metabolism

Constraint-based models of metabolism are a widely used framework for predicting flux distributions in genome-scale biochemical networks. The number of published methods for integration of transcriptomic data into constraint-based models has been rapidly increasing. So far the predictive capability...

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Detalles Bibliográficos
Autores principales: Machado, Daniel, Herrgård, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998872/
https://www.ncbi.nlm.nih.gov/pubmed/24762745
http://dx.doi.org/10.1371/journal.pcbi.1003580