Glutamate-Bound NMDARs Arising from In Vivo-like Network Activity Extend Spatio-temporal Integration in a L5 Cortical Pyramidal Cell Model

In vivo, cortical pyramidal cells are bombarded by asynchronous synaptic input arising from ongoing network activity. However, little is known about how such ‘background’ synaptic input interacts with nonlinear dendritic mechanisms. We have modified an existing model of a layer 5 (L5) pyramidal cell...

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Detalles Bibliográficos
Autores principales: Farinella, Matteo, Ruedt, Daniel T., Gleeson, Padraig, Lanore, Frederic, Silver, R. Angus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998913/
https://www.ncbi.nlm.nih.gov/pubmed/24763087
http://dx.doi.org/10.1371/journal.pcbi.1003590

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998913/
https://www.ncbi.nlm.nih.gov/pubmed/24763087
http://dx.doi.org/10.1371/journal.pcbi.1003590

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