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Inhibition of Breast Cancer Metastasis Suppressor 1 Promotes a Mesenchymal Phenotype in Lung Epithelial Cells That Express Oncogenic K-Ras(V12) and Loss of p53

Expression of the breast cancer metastasis suppressor 1 (BRMS1) protein is dramatically reduced in non-small cell lung cancer (NSCLC) cells and in primary human tumors. Although BRMS1 is a known suppressor of metastasis, the mechanisms through which BRMS1 functions to regulate cell migration and inv...

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Detalles Bibliográficos
Autores principales: Hall, Emily H., Liu, Yuan, Xiao, Aizhen, Shock, Lisa, Brautigan, David L., Mayo, Marty W., Adusumilli, Prasad S., Jones, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3999110/
https://www.ncbi.nlm.nih.gov/pubmed/24763730
http://dx.doi.org/10.1371/journal.pone.0095869