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Inhibition of Breast Cancer Metastasis Suppressor 1 Promotes a Mesenchymal Phenotype in Lung Epithelial Cells That Express Oncogenic K-Ras(V12) and Loss of p53
Expression of the breast cancer metastasis suppressor 1 (BRMS1) protein is dramatically reduced in non-small cell lung cancer (NSCLC) cells and in primary human tumors. Although BRMS1 is a known suppressor of metastasis, the mechanisms through which BRMS1 functions to regulate cell migration and inv...
Autores principales: | Hall, Emily H., Liu, Yuan, Xiao, Aizhen, Shock, Lisa, Brautigan, David L., Mayo, Marty W., Adusumilli, Prasad S., Jones, David R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3999110/ https://www.ncbi.nlm.nih.gov/pubmed/24763730 http://dx.doi.org/10.1371/journal.pone.0095869 |
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