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Loss of Function of Endothelin-2 Leads to Reduced Ovulation and CL Formation

Endothelin-2 (EDN2), a potent vasoconstrictive peptide, is transiently produced by periovulatory follicles at the time of ovulation when corpus luteum (CL) formation begins. EDN2 induces contraction of ovarian smooth muscles ex vivo via an endothelin receptor A-mediated pathway. In this study, we ai...

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Detalles Bibliográficos
Autores principales: Cacioppo, Joseph A., Oh, Sang Wook, Kim, Hey-young, Cho, Jongki, Lin, Po-Ching Patrick, Yanagisawa, Masashi, Ko, CheMyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3999112/
https://www.ncbi.nlm.nih.gov/pubmed/24763822
http://dx.doi.org/10.1371/journal.pone.0096115