Phosphatidylinositol-4,5-Bisphosphate Enhances Anionic Lipid Demixing by the C2 Domain of PKCα

The C2 domain of PKCα (C2α) induces fluorescence self-quenching of NBD-PS in the presence of Ca(2+), which is interpreted as the demixing of phosphatidylserine from a mixture of this phospholipid with phosphatidylcholine. Self-quenching of NBD-PS was considerably increased when phosphatidylinositol-...

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Detalles Bibliográficos
Autores principales: Egea-Jiménez, Antonio L., Fernández-Martínez, Ana M., Pérez-Lara, Ángel, de Godos, Ana, Corbalán-García, Senena, Gómez-Fernández, Juan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3999146/
https://www.ncbi.nlm.nih.gov/pubmed/24763383
http://dx.doi.org/10.1371/journal.pone.0095973

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3999146/
https://www.ncbi.nlm.nih.gov/pubmed/24763383
http://dx.doi.org/10.1371/journal.pone.0095973

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