HSCARG Negatively Regulates the Cellular Antiviral RIG-I Like Receptor Signaling Pathway by Inhibiting TRAF3 Ubiquitination via Recruiting OTUB1

RIG-I like receptors (RLRs) recognize cytosolic viral RNA and initiate innate immunity; they increase the production of type I interferon (IFN) and the transcription of a series of antiviral genes to protect the host organism. Accurate regulation of the RLR pathway is important for avoiding tissue i...

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Detalles Bibliográficos
Autores principales: Peng, Yanyan, Xu, Ruidan, Zheng, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3999155/
https://www.ncbi.nlm.nih.gov/pubmed/24763515
http://dx.doi.org/10.1371/journal.ppat.1004041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3999155/
https://www.ncbi.nlm.nih.gov/pubmed/24763515
http://dx.doi.org/10.1371/journal.ppat.1004041

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