Finding and Characterizing the Complexes of Drug Like Molecules with Quadruplex DNA: Combined Use of an Enhanced Hydroxyl Radical Cleavage Protocol and NMR

Structural information on the complexes of drug like molecules with quadruplex DNAs can aid the development of therapeutics and research tools that selectively target specific quadruplex DNAs. Screening can identify candidate molecules that require additional evaluation. An enhanced hydroxyl radical...

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Detalles Bibliográficos
Autores principales: Ranpura, Harikrushan, Bialonska, Dobroslawa, Bolton, Philip H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3999192/
https://www.ncbi.nlm.nih.gov/pubmed/24763734
http://dx.doi.org/10.1371/journal.pone.0096218

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3999192/
https://www.ncbi.nlm.nih.gov/pubmed/24763734
http://dx.doi.org/10.1371/journal.pone.0096218

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