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A simple method for the determination of reduction potentials in heme proteins

We describe a simple method for the determination of heme protein reduction potentials. We use the method to determine the reduction potentials for the PAS-A domains of the regulatory heme proteins human NPAS2 (E(m) = −115 mV ± 2 mV, pH 7.0) and human CLOCK (E(m) = −111 mV ± 2 mV, pH 7.0). We sugges...

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Detalles Bibliográficos
Autores principales: Efimov, Igor, Parkin, Gary, Millett, Elizabeth S., Glenday, Jennifer, Chan, Cheuk K., Weedon, Holly, Randhawa, Harpreet, Basran, Jaswir, Raven, Emma L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science B.V 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3999514/
https://www.ncbi.nlm.nih.gov/pubmed/24440354
http://dx.doi.org/10.1016/j.febslet.2013.12.030