DARC shuttles inflammatory chemokines across the blood–brain barrier during autoimmune central nervous system inflammation

The Duffy antigen/receptor for chemokines, DARC, belongs to the family of atypical heptahelical chemokine receptors that do not couple to G proteins and therefore fail to transmit conventional intracellular signals. Here we show that during experimental autoimmune encephalomyelitis, an animal model...

Descripción completa

Detalles Bibliográficos
Autores principales: Minten, Carsten, Alt, Carsten, Gentner, Melanie, Frei, Elisabeth, Deutsch, Urban, Lyck, Ruth, Schaeren-Wiemers, Nicole, Rot, Antal, Engelhardt, Britta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3999718/
https://www.ncbi.nlm.nih.gov/pubmed/24625696
http://dx.doi.org/10.1093/brain/awu045

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3999718/
https://www.ncbi.nlm.nih.gov/pubmed/24625696
http://dx.doi.org/10.1093/brain/awu045

Ejemplares similares