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DARC shuttles inflammatory chemokines across the blood–brain barrier during autoimmune central nervous system inflammation
The Duffy antigen/receptor for chemokines, DARC, belongs to the family of atypical heptahelical chemokine receptors that do not couple to G proteins and therefore fail to transmit conventional intracellular signals. Here we show that during experimental autoimmune encephalomyelitis, an animal model...
Autores principales: | Minten, Carsten, Alt, Carsten, Gentner, Melanie, Frei, Elisabeth, Deutsch, Urban, Lyck, Ruth, Schaeren-Wiemers, Nicole, Rot, Antal, Engelhardt, Britta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3999718/ https://www.ncbi.nlm.nih.gov/pubmed/24625696 http://dx.doi.org/10.1093/brain/awu045 |
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