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Computational Insights of the Interaction among Sea Anemones Neurotoxins and Kv1.3 Channel

Sea anemone neurotoxins are peptides that interact with Na(+) and K(+) channels, resulting in specific alterations on their functions. Some of these neurotoxins (1ROO, 1BGK, 2K9E, 1BEI) are important for the treatment of about 80 autoimmune disorders because of their specificity for Kv1.3 channel. T...

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Detalles Bibliográficos
Autores principales: Sabogal-Arango, Angélica, Barreto, George E, Ramírez-Sánchez, David, González-Mendoza, Juan, Barreto, Viviana, Morales, Ludis, González, Janneth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3999815/
https://www.ncbi.nlm.nih.gov/pubmed/24812496
http://dx.doi.org/10.4137/BBI.S13403