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Aza-Diels–Alder reaction between N-aryl-1-oxo-1H-isoindolium ions and tert-enamides: Steric effects on reaction outcome

The synthesis of 5-substituted 6,6a-dihydroisoindolo[2,1-a]quinolin-11(5H)-ones via [4 + 2] imino-Diels–Alder cyclization from N-aryl-3-hydroxyisoindolinones and N-vinyl lactams under Lewis acid-catalysed anhydrous conditions is reported. Reactions of N-(2-substituted-aryl)-3-hydroxyisoindolinones w...

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Detalles Bibliográficos
Autores principales: Jha, Amitabh, Chou, Ting-Yi, ALJaroudi, Zainab, Ellis, Bobby D, Cameron, T Stanley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3999823/
https://www.ncbi.nlm.nih.gov/pubmed/24778740
http://dx.doi.org/10.3762/bjoc.10.81