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Dihydrocapsaicin down-regulates apoM expression through inhibiting Foxa2 expression and enhancing LXRα expression in HepG2 cells

BACKGROUND: Apolipoprotein M (apoM), as a novel apolipoprotein which is mainly expressed in liver and kidney tissues, is associated with development and progression of atherosclerosis and diabetes. Our group have recently shown that Dihydrocapsaicin(DHC)can significantly decrease atherosclerotic pla...

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Detalles Bibliográficos
Autores principales: Zhao, Jia-Yi, Hu, Yan-Wei, Li, Shu-Fen, Hu, Ya-Rong, Ma, Xin, Wu, Shao-Guo, Wang, Yan-Chao, Gao, Ji-Juan, Sha, Yan-Hua, Zheng, Lei, Wang, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3999941/
https://www.ncbi.nlm.nih.gov/pubmed/24642298
http://dx.doi.org/10.1186/1476-511X-13-50