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ShatterProof: operational detection and quantification of chromothripsis

BACKGROUND: Chromothripsis, a newly discovered type of complex genomic rearrangement, has been implicated in the evolution of several types of cancers. To date, it has been described in bone cancer, SHH-medulloblastoma and acute myeloid leukemia, amongst others, however there are still no formal or...

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Detalles Bibliográficos
Autores principales: Govind, Shaylan K, Zia, Amin, Hennings-Yeomans, Pablo H, Watson, John D, Fraser, Michael, Anghel, Catalina, Wyatt, Alexander W, van der Kwast, Theodorus, Collins, Colin C, McPherson, John D, Bristow, Robert G, Boutros, Paul C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3999944/
https://www.ncbi.nlm.nih.gov/pubmed/24646301
http://dx.doi.org/10.1186/1471-2105-15-78