Trichostatin A, a histone deacetylase inhibitor, suppresses proliferation and epithelial–mesenchymal transition in retinal pigment epithelium cells

The proliferation and epithelial–mesenchymal transition (EMT) of retinal pigment epithelium (RPE) cells are the major pathological changes in development of proliferative vitreoretinopathy (PVR), which leads to severe visual impairment. Histone deacetylases (HDACs)-mediated epigenetic mechanisms pla...

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Detalles Bibliográficos
Autores principales: Xiao, Wei, Chen, Xiaoyun, Liu, Xialin, Luo, Lixia, Ye, Shaobi, Liu, Yizhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Ltd 2014
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4000116/
https://www.ncbi.nlm.nih.gov/pubmed/24456602
http://dx.doi.org/10.1111/jcmm.12212

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4000116/
https://www.ncbi.nlm.nih.gov/pubmed/24456602
http://dx.doi.org/10.1111/jcmm.12212

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