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Arecoline-induced myofibroblast transdifferentiation from human buccal mucosal fibroblasts is mediated by ZEB1

Oral submucous fibrosis (OSF) is considered as a pre-cancerous condition of the oral mucosa and is highly associated with habitual areca quid chewing. Arecoline is the major alkaloid in areca quid and is thought to be involved in the pathogenesis of OSF. Our previous studies have demonstrated that a...

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Detalles Bibliográficos
Autores principales: Chang, Yu-Chao, Tsai, Chung-Hung, Lai, You-Liang, Yu, Cheng-Chia, Chi, Wan-Yu, Li, Jung Jung, Chang, Wen-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4000120/
https://www.ncbi.nlm.nih.gov/pubmed/24400868
http://dx.doi.org/10.1111/jcmm.12219