TNF-α and IFN-γ gene variation and genetic susceptibility to type 1 diabetes and its microangiopathic complications

BACKGROUND: TNF-α has accelerating role in development of type 1 diabetes. Although an immunosupressor function and leading protecting role in T1DM also has been claimed for this pro-inflammatory cytokine. Over-expression of pro-inflammatory and type 1 cytokines (Th1, like IFN-γ) drive insulitis tow...

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Detalles Bibliográficos
Autores principales: Bazzaz, Javad Tavakkoly, Amoli, Mahsa M, Taheri, Zahra, Larijani, Bagher, Pravica, Vera, Hutchinson, Ian V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4000155/
https://www.ncbi.nlm.nih.gov/pubmed/24693923
http://dx.doi.org/10.1186/2251-6581-13-46

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4000155/
https://www.ncbi.nlm.nih.gov/pubmed/24693923
http://dx.doi.org/10.1186/2251-6581-13-46

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