Cargando…

Conformational Dynamics of DNA G-Quadruplex in Solution Studied by Kinetic Capillary Electrophoresis Coupled On-line with Mass Spectrometry**

G-quadruplex-forming DNA/RNA sequences play an important role in the regulation of biological functions and development of new anticancer and anti-aging drugs. In this work, we couple on-line kinetic capillary electrophoresis with mass spectrometry (KCE-MS) to study conformational dynamics of DNA G-...

Descripción completa

Detalles Bibliográficos
Autores principales: Mironov, Gleb G, Okhonin, Victor, Khan, Nasrin, Clouthier, Christopher M, Berezovski, Maxim V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley-VCH Verlag GmbH & Co 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4000168/
https://www.ncbi.nlm.nih.gov/pubmed/24808992
http://dx.doi.org/10.1002/open.201400002