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N-Aryl Isoleucine Derivatives as Angiotensin II AT(2) Receptor Ligands

A novel series of ligands for the recombinant human AT(2) receptor has been synthesized utilizing a fast and efficient palladium-catalyzed procedure for aminocarbonylation as the key reaction. Molybdenum hexacarbonyl [Mo(CO)(6)] was employed as the carbon monoxide source, and controlled microwave he...

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Detalles Bibliográficos
Autores principales: Behrends, Malte, Wallinder, Charlotta, Wieckowska, Anna, Guimond, Marie-Odile, Hallberg, Anders, Gallo-Payet, Nicole, Larhed, Mats
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley-VCH Verlag GmbH & Co 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4000169/
https://www.ncbi.nlm.nih.gov/pubmed/24808993
http://dx.doi.org/10.1002/open.201300040