Real-Time Bidirectional Pyrophosphorolysis-Activated Polymerization for Quantitative Detection of Somatic Mutations

Detection of somatic mutations for targeted therapy is increasingly used in clinical settings. However, due to the difficulties of detecting rare mutations in excess of wild-type DNA, current methods often lack high sensitivity, require multiple procedural steps, or fail to be quantitative. We devel...

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Detalles Bibliográficos
Autores principales: Song, Najie, Zhong, Xueting, Li, Qingge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4000192/
https://www.ncbi.nlm.nih.gov/pubmed/24769870
http://dx.doi.org/10.1371/journal.pone.0096420

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4000192/
https://www.ncbi.nlm.nih.gov/pubmed/24769870
http://dx.doi.org/10.1371/journal.pone.0096420

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