Rac2 Controls Tumor Growth, Metastasis and M1-M2 Macrophage Differentiation In Vivo

Although it is well-established that the macrophage M1 to M2 transition plays a role in tumor progression, the molecular basis for this process remains incompletely understood. Herein, we demonstrate that the small GTPase, Rac2 controls macrophage M1 to M2 differentiation and the metastatic phenotyp...

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Detalles Bibliográficos
Autores principales: Joshi, Shweta, Singh, Alok R., Zulcic, Muamera, Bao, Lei, Messer, Karen, Ideker, Trey, Dutkowski, Janusz, Durden, Donald L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4000195/
https://www.ncbi.nlm.nih.gov/pubmed/24770346
http://dx.doi.org/10.1371/journal.pone.0095893

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4000195/
https://www.ncbi.nlm.nih.gov/pubmed/24770346
http://dx.doi.org/10.1371/journal.pone.0095893

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