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Genetic Variants in MicroRNA Machinery Genes Are Associate with Idiopathic Recurrent Pregnancy Loss Risk

OBJECTIVE: Key molecules involved in microRNA (miRNA) biogenesis, such as DROSHA, XPO5, and DICER, have been identified in trophoblast cells, confirming that the miRNA biogenesis pathway is active in human placenta. In addition, miRNAs regulate uterine gene expression associated with inflammatory re...

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Detalles Bibliográficos
Autores principales: Jung, Yong Wook, Jeon, Young Joo, Rah, HyungChul, Kim, Ji Hyang, Shin, Ji Eun, Choi, Dong Hee, Cha, Sun Hee, Kim, Nam Keun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4000197/
https://www.ncbi.nlm.nih.gov/pubmed/24769857
http://dx.doi.org/10.1371/journal.pone.0095803