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Conversion from twice- to once-daily tacrolimus in pediatric kidney recipients: a pharmacokinetic and bioequivalence study

BACKGROUND: The objectives of this study were to investigate pharmacokinetic and pharmacogenetic parameters during the conversion on a 1:1 (mg:mg) basis from a twice-daily (Prograf) to once-daily (Advagraf) tacrolimus formulation in pediatric kidney transplant recipients. METHODS: Twenty-four-hour p...

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Detalles Bibliográficos
Autores principales: Lapeyraque, Anne-Laure, Kassir, Nastya, Théorêt, Yves, Krajinovic, Maja, Clermont, Marie-José, Litalien, Catherine, Phan, Véronique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4000411/
https://www.ncbi.nlm.nih.gov/pubmed/24435759
http://dx.doi.org/10.1007/s00467-013-2724-0