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Double-blind, placebo-controlled, randomized phase II study of TJ-14 (hangeshashinto) for gastric cancer chemotherapy-induced oral mucositis

BACKGROUND: Hangeshashinto (TJ-14, a Kampo medicine), which reduces the level of prostaglandin E2 and affects the cyclooxygenase activity, alleviates chemotherapy-induced oral mucositis (COM). We conducted a randomized comparative trial to investigate whether TJ-14 prevents and controls COM in patie...

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Detalles Bibliográficos
Autores principales: Aoyama, Toru, Nishikawa, Kazuhiro, Takiguchi, Nobuhiro, Tanabe, Kazuaki, Imano, Motohiro, Fukushima, Ryoji, Sakamoto, Junichi, Oba, Mari S., Morita, Satoshi, Kono, Toru, Tsuburaya, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4000413/
https://www.ncbi.nlm.nih.gov/pubmed/24652604
http://dx.doi.org/10.1007/s00280-014-2440-x