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Oxysterols in the brain of the cholesterol 24-hydroxylase knockout mouse
Oxysterols are oxidised forms of cholesterol or its precursors. In this study we utilised the cholesterol 24-hydroxylase knockout mouse (Cyp46a1−/−) to study the sterol and oxysterol content of brain. Despite a great reduction in the abundance of 24S-hydroxycholesterol, the dominant metabolite of ch...
Autores principales: | Meljon, Anna, Wang, Yuqin, Griffiths, William J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4000437/ https://www.ncbi.nlm.nih.gov/pubmed/24491562 http://dx.doi.org/10.1016/j.bbrc.2014.01.153 |
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