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Enhanced circulating PCSK9 concentration by berberine through SREBP-2 pathway in high fat diet-fed rats
BACKGROUND: Berberine (BBR), a natural plant extract, has been shown to improve lipid metabolism. However, its effects on PCSK9, a key factor involving in the lipid metabolism, have not yet been evaluated in vivo. The aim of the present study was to investigate the effect of BBR on PCSK9 expression...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4000533/ https://www.ncbi.nlm.nih.gov/pubmed/24755036 http://dx.doi.org/10.1186/1479-5876-12-103 |