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Sitagliptin Prevents Inflammation and Apoptotic Cell Death in the Kidney of Type 2 Diabetic Animals

This study aimed to evaluate the efficacy of sitagliptin, a dipeptidyl peptidase IV (DPP-IV) inhibitor, in preventing the deleterious effects of diabetes on the kidney in an animal model of type 2 diabetes mellitus; the Zucker diabetic fatty (ZDF) rat: 20-week-old rats were treated with sitagliptin...

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Detalles Bibliográficos
Autores principales: Marques, Catarina, Mega, Cristina, Gonçalves, Andreia, Rodrigues-Santos, Paulo, Teixeira-Lemos, Edite, Teixeira, Frederico, Fontes-Ribeiro, Carlos, Reis, Flávio, Fernandes, Rosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4000968/
https://www.ncbi.nlm.nih.gov/pubmed/24817793
http://dx.doi.org/10.1155/2014/538737