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Structure-Functional Prediction and Analysis of Cancer Mutation Effects in Protein Kinases

A central goal of cancer research is to discover and characterize the functional effects of mutated genes that contribute to tumorigenesis. In this study, we provide a detailed structural classification and analysis of functional dynamics for members of protein kinase families that are known to harb...

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Detalles Bibliográficos
Autores principales: Dixit, Anshuman, Verkhivker, Gennady M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4000980/
https://www.ncbi.nlm.nih.gov/pubmed/24817905
http://dx.doi.org/10.1155/2014/653487