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Structure-Functional Prediction and Analysis of Cancer Mutation Effects in Protein Kinases
A central goal of cancer research is to discover and characterize the functional effects of mutated genes that contribute to tumorigenesis. In this study, we provide a detailed structural classification and analysis of functional dynamics for members of protein kinase families that are known to harb...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Hindawi Publishing Corporation
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4000980/ https://www.ncbi.nlm.nih.gov/pubmed/24817905 http://dx.doi.org/10.1155/2014/653487 |